Parsons Corporation Laboratory Manager in Frederick, Maryland
Minimum Clearance Required to Start:
We are committed to solving the Military Health System's most challenging health and operational readiness issues with the world's best data-driven solutions. Our staff supports a myriad of mission-critical science and technology projects for all military Services, both in the U.S. and around the globe. Our core competencies include Research and Program Management in the areas of Infectious Diseases, Clinical and Rehabilitative Medicine, Genomics-based Science, and Military Health, Performance, and Recovery. Parsons Health: We are committed to using innovation to drive the greatest value for our customers.
Parsons is seeking well qualified applicants for a Laboratory Manager with the Genomics and Bioinformatics Department of the Biological Defense Research Directorate (BDRD). Headquartered in Fort Detrick, Maryland, BDRD is part of the Naval Medical Research Center. Their mission is to apply bioinformatics and cutting edge, high-throughput technologies such as genotypic and phenotypic expression profiling, biomarker characterization, bacteriophage science, etc. to the study of infectious diseases, biodefense, and enhanced global disease surveillance for early pathogen detection and response.
Provide practical knowledge of basic and applied research, including experimental design and methods, and shall possess the demonstrated ability to perform original and competent research.
Support research that conducts high throughput 'omics' analyses of pathogens, near neighbors, and environmental samples, to include biosurveillance, pathogen discovery, and biomarker characterization.
Utilize existing laboratory personnel and assets to provide general laboratory support, including BSL-2 and BSL-3 capabilities.
Conduct validation studies and provide general laboratory evaluations utilizing organisms of interest requiring BSL-2 and BSL-3 controls.
Perform whole genome sequencing of samples using the MiSeq, NextSeq500, Ion Torrent, or MinION platform as appropriate given chemistry constraints and output desired, for bacteriophage and other (bacterial host, etc.) genomes.
Contribute high quality reference sequences to improve the comparator databases.
Provide support in Probe/Primer design, assessment of sensitivity and specificity, surveying pathogens in environments and clinical samples.
Support whole genome sequencing of complex samples (e.g. swabs, stool, etc.) and isolates using unbiased shotgun sequencing, amplicon sequencing, enrichment sequencing and/or a combination of approaches as required.
Testing and evaluation of new protocols to include; generation of coding complete genomes using in silico closure methods, phylogenetic and molecular epidemiological analyses.
Preparation of data files and submission to databases as appropriate.
Support verification and validation of countermeasures against emerging pathogens
Securely store data files and provide final results to customer, and if requested, raw data files.
Track research related resources including expenses/budget, supplies, and laboratory inventories (subject to final Government approval/confirmation and shall not include inherently governmental functions).
Master's or Bachelor's degree (combined with laboratory management experience) degree in the field of biological sciences or relevant field.
5 years practical experience conducting microbiology/molecular biology techniques in a BSL-2 or BSL-3 laboratory and 2 years' experience managing all aspects of a laboratory facility including chemical hygiene, hazardous waste.
demonstrated ability to manage a BSL-2 or BSL-3 laboratory, including training of contractor scientists, contractor technicians, and contractor support personnel, writing standard operating procedures/risk assessments (subject to final Government approval)
Knowledge and understanding of Federal and DoD laboratory regulations/instructions such as DOD Manual 6055.18, Safety Standards for Microbiological and Biomedical Laboratories, and Center for Disease Control Biosafety in Microbiological and Biomedical Laboratories (BMBL), current edition available at https://www.cdc.gov/labs/pdf/CDC-BiosafetyMicrobiologicalBiomedicalLaboratories-2020-P.pdf, is essential.
Shall pass all criteria for a Secret security clearance.
Must be able to obtain, maintain and/or currently possess a security clearance.
Parsons is an equal opportunity, drug-free employer committed to diversity in the workplace. Minority/Female/Disabled/Protected Veteran/LGBTQ+. All qualified applicants will receive consideration for employment without regard to an individual’s race, color, religion, national origin, ethnicity, union affiliation, age, sex, sexual orientation, gender identity and expression, pregnancy, employable physical or mental disability, veteran status, genetic information, immigration status, or any other basis protected by all applicable laws.